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The model also found that because younger men are more likely to be cured of their precancer without intervention, patients younger than 29 should not be treated and those between 29 and 38 years old should be actively monitored (watch-and-wait approach) in order to prevent treatment-related inconvenience and morbidity that might affect their quality of life.
Currently, HPV vaccination is not recommended for administration among individuals 27 years or older.
Almost 620,000 gay and bisexual men in the United States were living with HIV in 2014, and 100,000 of these men were not even aware of their infection.
These men are 100 times more likely to have anal cancer than HIV-negative men who exclusively have sex with women.
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Please add a one-time donation to help fund our most urgent campaigns to fight discrimination and expand LGBTQ rights.Some in the medical community have identified anal cancer as the next big crisis among HIV-infected gay and bisexual men.Initiation of anti-retroviral therapy in the 1990s greatly reduced the AIDS-related death rate and improved survival.We followed these hypothetical patients over their lifetime in our computer model to estimate harms and benefits of the management strategies.We tracked the number of individuals who developed anal cancer and then estimated their risk of death from anal cancer. For each strategy, we estimated age-specific lifetime outcomes considering cost, quality of life and life expectancy.